Immunohistochemistry Kits and Reagents
Cayman Chemical S-p38 MAPK InhIbItr III 500ug
A methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro); potently blocks the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively)
ABclonal Technology TFF1/pS2 Rabbit mAb
Members of the trefoil family are characterized by having at least one copy of the trefoil motif a 40-amino acid domain that contains three conserved disulfides They are stable secretory proteins expressed in gastrointestinal mucosa Their functions are not defined but they may protect the mucosa from insults stabilize the mucus layer and affect healing of the epithelium This gene which is expressed in the gastric mucosa has also been studied because of its expression in human tumors This gene and two other related trefoil family member genes are found in a cluster on chromosome 21
Genetex Inc Calbindin Monoclonal Antibody [HMV326] HistoMAX™ (GTX640558) GeneTex - IHC-Optimized Antibody
The Calbindin antibody [HMV326] HistoMAX™ (GTX640558) is a Rabbit Monoclonal antibody in the GeneTex HistoMAX portfolio. The antibody is extensively evaluated for IHC-P using formalin-fixed human normal tissues (more than 70 different sections) and cancer tissue arrays to guarantee specificity and best-in-class performance. Information regarding both manual and autostainer staining protocols are available.Figure Legend: IHC-P analysis of human cerebellum cortex tissue (molecular layer, Purkinje cell layer, and granule cell layer) using GTX640558 Calbindin antibody [HMV326] HistoMAX. Strong Calbindin staining of Purkinje cells and of associated axonal fibres.
ABclonal Technology 488 Conjugated AIF1/IBA1
Enables actin filament binding activity and calcium ion binding activity Involved in several processes including Rac protein signal transduction actin filament organization and ruffle assembly Acts upstream of or within actin filament bundle assembly Located in several cellular components including actin filament phagocytic cup and ruffle membrane Is expressed in adrenal cortex central nervous system embryo mesenchyme and retina Human ortholog(s) of this gene implicated in type 1 diabetes mellitus Orthologous to human AIF1 (allograft inflammatory factor 1)
Abcam Mouse and Rabbit Specific HRP/DAB IHC Detection Kit - Micro-polymer, 125ML
Rabbit/mouse dual, HRP/DAB detection IHC kit is a colorimetric micro-polymer assay kit used to detect mouse and rabbit primary antibodies in immunohistochemistry (IHC). - Cited in over 65 publications - No need for endogenous biotin blocking - Includes ready-to-use blocking reagents - Higher sensitivity than streptavidin-biotin methods
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Human Phospho-STAT6 (Tyr641 & total) Detection Kit, Control Lysate
AlphaLISA SureFire Ultra Multiplex Human Phospho-STAT6 (Tyr641 & total) Detection Kit, Control Lysate
FUJIFILM BIOSCIENCES INC Anti Human Podocalyxin Monoclo
Podocalyxin is a member of the CD34 family of type I transmembrane sialomucins It is expressed in many normal cells such as renal podocytes and endothelial cells It is also expressed in many types of tumors including colorectal cancers breast cancers and brain tumors Overexpression of podocalyxin is an independent predictor of progression metastasis and poor prognosis Recent studies indicate that the glycosylation of podocalyxin change depending on the state of the cells This antibody recognized endogenous podocalyxin expressing cancer cell lines and normal cells independently of glycosylation
Abcam Mouse and Rabbit Specific HRP/DAB IHC Detection Kit - Micro-polymer, 15ML
Rabbit/mouse dual, HRP/DAB detection IHC kit is a colorimetric micro-polymer assay kit used to detect mouse and rabbit primary antibodies in immunohistochemistry (IHC). - Cited in over 65 publications - No need for endogenous biotin blocking - Includes ready-to-use blocking reagents - Higher sensitivity than streptavidin-biotin methods
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical p38 MAPK PhosphoThr180 Tyr18
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK • Host: rabbit • Cross Reactivity: (+) human p38 MAPK • Application(s): WB • p38 MAPK is activated by both inflammatory cytokines and by stress. It is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
ABclonal Technology ALKBH5 Rabbit mAb
Enables mRNA N6-methyladenosine dioxygenase activity Involved in RNA metabolic process mRNA export from nucleus and response to hypoxia Located in Golgi apparatus cytosol and nuclear speck ALKBH5 also named as ABH5 and OFOXD1 is a Dioxygenase that demethylates RNA by oxidative demethylation It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo ALKBH5 is required for spermatogenesis
ABclonal Technology Phospho-TDP-43/TARDBP-S409/S410 Rabbit pAb
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Abcam 2 mm Coronal Mouse Brain Slicer, 1UNIT
This 2 mm coronal mouse brain slicer allows you to easily cut a brain into smaller pieces for easier imaging with objectives that have a limited working distance.
The product is subject to the following: Abcam Restricted Use Statement
Seracare Life Sciences Inc BLOCKING SOLUTION CONCENTRATE
Blocking solution concentrate is used in immunohistochemistry applications where endogenous peroxidase activity causes non-specific signal and high background. Supplied as a 10X concentrate; working solution is prepared by diluting 1:10 in reagent quality water. Also available as part of HistoMark TrueBlue, HistoMark ORANGE and HistoMark BLACK substrate kits.
Abcam DoubleStain IHC kit: G&M on human tissue (BCIP & AEC), 18ML
The DoubleStain IHC kit (ab183271) is designed to use with user supplied goat and mouse antibodies to detect two distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement